Apolipoprotein A1 (apoA1) is the main protein component of high density lipoprotein particles (HDL). ApoA1 (28 kD) is mainly produced in the liver and exported into the circulation where it acquires lipids and becomes HDL. High level of apoA1 is regarded as protective against atherosclerosis and cardiovascular disease. Normal concentration in plasma is 1-2 mg/ml.
All kits include purified human apoA1 as a standard calibrated against an international standard (WHO).
Cross-reactivity has been assessed and confirmed with certain non-human primate species.
Mabtech’s enzyme-linked immunosorbent assay, ELISA PRO, is a complete kit for the quantification of human apoA1 in biological fluids such as serum, plasma and cell culture supernatants. The assay utilizes ELISA strip plates precoated with capture monoclonal antibodies (mAb), a biotinylated mAb for detection, streptavidin-horseradish peroxidase (SA-HRP), TMB substrate, standard, buffers, diluents, stop solution and adhesive plate covers.