Interleukin-21 (IL-21) is primarily secreted by CD4+ T cells (in particular follicular T cells and Th17) and is an important regulator of immune responses; for Th17 cells, IL-21 is an autocrine regulator sustaining Th17 development. IL-21 also regulates the development of other T cells as well as B cells, NK cells and dendritic cells. Areas of particular interest for research on IL-21 include autoimmune and inflammatory diseases, cancer research but also basic studies on e.g. B cells and T cells, in particular Th17 cells.
Mouse monoclonal antibody specific for human IL-21. Suitable as detection antibody in ELISA and ELISpot in combination with mAbs MT21.4/821 (product code 3540-3).
京公网安备11010802025653 版权所有：北京逸优科技有限公司
