Granzyme B is a serine protease released by the cytoplasmic granules within cytotoxic T cells and NK cells. Granzyme B will act in concert with perforin and other cytotoxic mediators to induce target cell death by apoptosis.
Mouse monoclonal antibody to human Granzyme B, clone GB11 biotinylated. Suitable as detection antibody in ELISA and ELISpot in combination with clone GB10, code 3485-3).