Granulocyte macrophage-colony stimulating factor (GM-CSF) can be produced by several cell types among others activated T cells, macrophages, endothelial cells and stromal cells. GM-CSF stimulates the survival and functional activities of neutrophils, eosinophils, and monocyte-macrophages. It also stimulates the differentiation and proliferation of hematological progenitors.
Reacts with Human, cross reacts with certain non-human primates. Neutralizing antibodies have only been tested with human cells.
Rat monoclonal antibody to human GM-CSF, clone 23B6 biotinylated, suitable as detection antibody in ELISA and ELISpot (in combination with clone 21C11, code 3480-3).
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