Perforin is produced by cytotoxic T cells and NK cells as an effector molecule in the cell-mediated destruction of target cells. Perforin will facilitate delivery of granzymes which induces apoptosis of the target cell.
Cross-reactivity has been assessed and confirmed with certain non-human primate species.
ELISpot PLUS kit for the detection of human or monkey Perforin. This complete kit contains precoated white ELISpot plates, biotinylated detection antibody, Streptavidin-ALP and BCIP/NBT substrate. Combines excellent performance with rapid procedure and high reproducibility. Assay time is approximately 4,5 hours excluding cell incubation time.
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