Perforin is produced by cytotoxic T cells and NK cells as an effector molecule in the cell-mediated destruction of target cells. Perforin will facilitate delivery of granzymes which induces apoptosis of the target cell.
Cross-reactivity has been assessed and confirmed with certain non-human primate species.
ELISpot PLUS kit for the detection of human or monkey Perforin. This complete kit contains ELISpot plates with PVDF membrane, monoclonal capture antibody, monocl. biotin. detection antibody, Streptavidin-ALP and BCIP/NBT substrate.