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Rabbit anti-mouse IgM-ALP

  • 产品编号:3310-13      品牌:Mabtech       原厂货号:3310-13
  • 产品分类:抗体 > 二抗 > 酶标记
  • 应用分类:
 
包装: 1 ml
运保温度: Ambient
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描述:

Monomeric IgM (Immunoglobulin M) is found on the surface of B cells whereas the IgM molecules secreted from plasma B cells are pentamers, i.e. five IgM molecules joined together by the J chain. IgM constitutes approximately 10% of the total Ig concentration in serum. IgM is the first antibody isotype induced in a typical immune response and hence is the isotype with the lowest affinity for antigens. Due to its structure, with 10 antigen-binding sites per IgM pentamer, it can nevertheless bind e.g. surface-bound antigens with a very high avidity.
 


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