Interferon-γ (IFN-γ) is produced mainly by activated T cells and NK cells. It is a proinflammatory cytokine that activates macrophages and endothelial cells, but it also regulates immune responses by effecting APC and T and B cells. Production of IFN-γ by helper T cells as well as cytotoxic T cells is a hallmark of the TH1-type phenotype, thus, high-level production of IFN-γ is typically associated with effective host defense against intracellular pathogens.
The monoclonal antibody mentioned below are suitable for the detection of IFN-γ in pig.
Mouse monoclonal antibody to porcine Interferon-γ, clone pIFNγ-I. Suitable as capture antibody in ELISA and ELISpot (in combination with clone PAN biotinylated, code 3115-6).