Interleukin-4 (IL-4) is produced by activated T cells, especially differentiated CD4+ TH2-type cells, and stimulated mast cells and basophils. The most important effects of IL-4 are the regulation of helper T cell differentiation to the TH2 type and the regulation of IgE and IgG4 production by B cells.
The monoclonal antibodies mentioned below are suitable for the detection of IL-4 in cow and sheep.
Mouse monoclonal antibody to bovine IL-4. Suitable as capture antibody in ELISA and ELISpot in combination with detection mAb bIL4-II.