1910-8000F is specific for Cathepsin B, a lysosomal protease expressed in a wide range of tissues, including liver, skeletal muscle and heart.
Cathepsin B plays a role in protein degradation and has also been shown to activate urokinase type plasminogen activator (uPA) and certain matrix metalloproteinases (MMPs).
While raised against human Cathepsin B, it is likely that 1910-8000F will cross react with Cathepsin B from other species.
Application
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visitwww.abdserotec.com/protocols.
Application Name
Yes
No
Not Determined
Suggested Dilution
ELISA
1/1000 - 1/10000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
Storage
Store at +4oC or at -20oC if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
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