Affinity Purified Recombinant human CD40 Ligand 25 ug

产品编号：14-8502-80 品牌：eBioscience 原厂货号：14-8502-80
产品分类：蛋白质检测与分析 > 蛋白质，多肽和酶 > CD因子及其它细胞表面标记分子
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than or equal to -70°C

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描述：

Description: CD40 ligand, (CD40L, also known as CD154, TRAP or gp39) is a membrane glycoprotein expressed on activated CD4+ T-cells, NK cells, mast cells, basophils and eosinophils. The CD40-CD40L interaction stimulates B cell immune response which includes cell surface antigen expression, cell cycle activation, Ig isotype switching, Ig secretion and memory generation. The CD40-CD40L interaction also plays important roles in monocyte and dendritic cell activation, T-cell co-stimulation and cytokine production. It has been reported that the CD40-CD40L interaction is involved in the pathogenesis of amyloid pathology in Alzheimer disease.

Recombinant Human CD40L produced in E.Coli is a non-glycosylated, polypeptide containing 149 amino acids and having a molecular mass of 16 kDa.