Description: The rabbit polyclonal antibody reacts with mouse IL-15. The antibody was generated using E. coli expressed mouse IL-15 as an immunogen. IL-15 is a 14-15 kDa member of the four alpha-helical bundle family of cytokines. It is very similar to IL-2, except that IL-15 has an IL-15α receptor subunit. It plays an important role in the growth and differentiation of T and B lymphocytes, natural killer cells, macrophages, and monocytes as well as activation of a number of important intracellular signaling molecules. This implies that IL-15 could be essential for the immune responses, allograft rejection, and the pathogenesis of autoimmune diseases.
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