Description: The 16a11 monoclonal antibody reacts with the mouse NKG2AB6. NKG2 molecules belong to a C-type lectin-like family of cell surface receptors expressed by mouse NK and NKT cell lineages. NKG2 molecules form heterodimeric complexes with CD95 and are responsible for recognition of non-classical MHC class I antigen Qa-1. This antibody reacts with the C57Bl/6 mouse strain, but does not react with the BALB/c or 129 mouse strains.
When co-staining with NKG2A/C/E clone 20d5, it is important to stain for NKG2AB6 first then subsequently with NKG2A/C/E, as steric hindrance has been observed if co-stained concurrently.