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Purified Mouse/human Oct-2 (clone 9A2), 100 ug

  • 产品编号:14-5840-82      品牌:eBioscience       原厂货号:14-5840-82
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
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运保温度: 2-8℃
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描述:

Description: This monoclonal 9A2 antibody recognizes human and mouse Oct2, a transcription factor that binds conserved octamer DNA motifs within immunoglobulin promoters. The structure of the Oct2 protein consists of an amino terminal glutamine-rich domain, a central POU homeodomain and a carboxy terminal transactivation domain. Predominantly expressed in the nucleus of B cells, Oct2 has also been found in activated T cells and a subset of myeloid cells. Based on knock-out studies, expression is not required for B cell commitment but is required for maturation. In addition to developmental expression, Oct2 has been associated with neoplasm and maybe a useful tool for characterization of DLBCL and classical Hodgkin’s disease.


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