Description: The HIP8 monoclonal antibody reacts with the human CD41 molecule, the integrin αIIb also known as platelet GPIIb. CD41 non-covalently associates with integrin β3 (GPIIIa, CD61) and is expressed by megakaryocytes and platelets. The CD41/CD61 complex is a receptor for fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin and mediates platelets aggregation. HIP8 blocks platelet aggregation.
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