Clone REA893 recognizes the rat MZB1 antigen, a marginal zone B- and B1-cell–specific protein. Marginal zone B cells are noncirculating mature B cells, that are located in the spleen. In association with heavy and light chains of IgM MZB1 mediates IgM secretion and assembly. Furthermore, MZB1 functions as a proinflammatory cytokine that is involved in chronic inflammation and in affecting cellular expansion.
Additional information: Clone REA893 displays negligible binding to Fc receptors.
Alternative Names
Pacap
原厂资料：
Clone REA893 recognizes the rat MZB1 antigen, a marginal zone B- and B1-cell–specific protein. Marginal zone B cells are noncirculating mature B cells, that are located in the spleen. In association with heavy and light chains of IgM MZB1 mediates IgM secretion and assembly. Furthermore, MZB1 functions as a proinflammatory cytokine that is involved in chronic inflammation and in affecting cellular expansion.
Additional information: Clone REA893 displays negligible binding to Fc receptors.
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