Clone REA869 recognizes the mouse transcription factor EGR-2, also known as early growth response protein 2 or Krox20. EGR-2 consists of three tandem C2H2-type zinc fingers and its expression is induced by EGFR, which is important for osteoprogenitor maintenance and new bone formation. EGR-2 is found primarily in adult thymus, in the embryonic nervous system, and in mammary tumors and plays a critical role in the development of T cells and NKT cells.
Additional information: Clone REA869 displays negligible binding to Fc receptors.
原厂资料：
Clone REA869 recognizes the mouse transcription factor EGR-2, also known as early growth response protein 2 or Krox20. EGR-2 consists of three tandem C2H2-type zinc fingers and its expression is induced by EGFR, which is important for osteoprogenitor maintenance and new bone formation. EGR-2 is found primarily in adult thymus, in the embryonic nervous system, and in mammary tumors and plays a critical role in the development of T cells and NKT cells.
Additional information: Clone REA869 displays negligible binding to Fc receptors.
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