Clone REA793 recognizes both alloantigeneic forms of the mouse CD8b antigen, a single-pass type I membrane protein also known as lymphocyte antigen 3 (Ly-3 or Lyt-3). The CD8 molecule is composed of two distinct polypeptide chains that pair on the cell surface either as a CD8aa homodimer or as a CD8ab heterodimer. These forms of the CD8 molecule are differentially expressed on functionally distinct CD8
+
lymphocyte subsets. The CD8ab heterodimer is expressed on cytotoxic T cells and thymocytes.
Additional information: Clone REA793 displays negligible binding to Fc receptors.Alternative Names
Cd8b1, Ly-3, Ly-C, Lyt-3
原厂资料：
Clone REA793 recognizes both alloantigeneic forms of the mouse CD8b antigen, a single-pass type I membrane protein also known as lymphocyte antigen 3 (Ly-3 or Lyt-3). The CD8 molecule is composed of two distinct polypeptide chains that pair on the cell surface either as a CD8aa homodimer or as a CD8ab heterodimer. These forms of the CD8 molecule are differentially expressed on functionally distinct CD8
+
lymphocyte subsets. The CD8ab heterodimer is expressed on cytotoxic T cells and thymocytes.
Additional information: Clone REA793 displays negligible binding to Fc receptors.Alternative Names
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