Clone REA761 recognizes the human CD61 antigen, a cell surface protein belonging to the integrin family. CD61 is also known as the integrin β3-subunit. It associates with CD41 to form the heterodimeric gpIIb/gpIIIa complex that is present on human megakaryocytes and platelets and mediates cell adhesion processes. Together with CD51, CD61 forms the vitronectin receptor, which is present on platelets as well as on a variety of other cell types such as osteoclasts and endothelial vessel cells. Clone REA761 specifically recognizes the integrin β3-chain of both heterodimeric complexes.
Additional information: Clone REA761 displays negligible binding to Fc receptors.
Alternative Names
ITGB3, BDPLT16, BDPLT2, GP3A, GPIIIa, GT
原厂资料：
Clone REA761 recognizes the human CD61 antigen, a cell surface protein belonging to the integrin family. CD61 is also known as the integrin β3-subunit. It associates with CD41 to form the heterodimeric gpIIb/gpIIIa complex that is present on human megakaryocytes and platelets and mediates cell adhesion processes. Together with CD51, CD61 forms the vitronectin receptor, which is present on platelets as well as on a variety of other cell types such as osteoclasts and endothelial vessel cells. Clone REA761 specifically recognizes the integrin β3-chain of both heterodimeric complexes.
Additional information: Clone REA761 displays negligible binding to Fc receptors.
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