Clone 13G3 recognizes the mouse CD352 antigen, a single-pass type I membrane protein, also known as SLAM family member 6 (SLAM6) or NK, T, and B cell antigen (NTB-A) belonging to the CD2 subfamily of the immunoglobulin superfamily. It is expressed on NK, T, and B cells. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases. CD352 plays a role in NK cell cytotoxicity and T cell cytokine responses. It controls neutrophil functions and serves as a regulator of both innate and adaptive immune responses.
Alternative names
SLAM Family Receptor, SLAMF6, SLAM F6, LY108, Lymphocyte antigen 108, SLAM family member 6
原厂资料:
Clone 13G3 recognizes the mouse CD352 antigen, a single-pass type I membrane protein, also known as SLAM family member 6 (SLAM6) or NK, T, and B cell antigen (NTB-A) belonging to the CD2 subfamily of the immunoglobulin superfamily. It is expressed on NK, T, and B cells. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases. CD352 plays a role in NK cell cytotoxicity and T cell cytokine responses. It controls neutrophil functions and serves as a regulator of both innate and adaptive immune responses.
Alternative names
SLAM Family Receptor, SLAMF6, SLAM F6, LY108, Lymphocyte antigen 108, SLAM family member 6