Clone 53-6.7 is specific for the mouse CD8a (Ly-2) antigen, which is expressed on cytotoxic T cells and at lower levels on subpopulations of dendritic cells and TCRγ/δ+ cells. It is further detected on most thymocytes (CD4+CD8a+ and CD4–CD8+ thymocytes). Cytotoxic T cells and thymocytes express CD8a as heterodimer with CD8b, whereas dendritic cells and TCRγ/δ+ cells express a CD8a/CD8a homodimer.
原厂资料:
Clone 53-6.7 is specific for the mouse CD8a (Ly-2) antigen, which is expressed on cytotoxic T cells and at lower levels on subpopulations of dendritic cells and TCRγ/δ+ cells. It is further detected on most thymocytes (CD4+CD8a+ and CD4–CD8+ thymocytes). Cytotoxic T cells and thymocytes express CD8a as heterodimer with CD8b, whereas dendritic cells and TCRγ/δ+ cells express a CD8a/CD8a homodimer.