CD138, also known as syndecan-1, is a type I integral membrane protein belonging to the syndecan protein family which carries three to five heparan sulfate and chondroitin sulfate chains. CD138 is highly expressed on plasma cells and pre–B cells but not on mature peripheral B cells. It is also expressed on fibroblasts and epithelial cells. The expression of CD138 can be regulated by several cytokines and factors, e.g., thrombin, which is reported to increase the synthesis of CD138 molecules that exhibit high-affinity antithrombin-3 binding.
原厂资料：
CD138, also known as syndecan-1, is a type I integral membrane protein belonging to the syndecan protein family which carries three to five heparan sulfate and chondroitin sulfate chains. CD138 is highly expressed on plasma cells and pre–B cells but not on mature peripheral B cells. It is also expressed on fibroblasts and epithelial cells. The expression of CD138 can be regulated by several cytokines and factors, e.g., thrombin, which is reported to increase the synthesis of CD138 molecules that exhibit high-affinity antithrombin-3 binding.
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