Langerin (CD207 antigen), a 40 kDa, glycosylated type II transmembrane C-type lectin receptor, is the standard marker for human and murine Langerhans cells (LCs).
LCs are a subset of dendritic cells (DCs) cells that reside in epithelia; the best studied example of these antigen-presenting cells are LCs of the epidermis.
CD207 is directly involved in antigen capture as well as endocytosis and induces the formation of typical Birbeck granules in immature DCs.
原厂资料：
Langerin (CD207 antigen), a 40 kDa, glycosylated type II transmembrane C-type lectin receptor, is the standard marker for human and murine Langerhans cells (LCs).
LCs are a subset of dendritic cells (DCs) cells that reside in epithelia; the best studied example of these antigen-presenting cells are LCs of the epidermis.
CD207 is directly involved in antigen capture as well as endocytosis and induces the formation of typical Birbeck granules in immature DCs.
京公网安备11010802025653 版权所有：北京逸优科技有限公司
