CD324-PE (E-Cadherin), human 30 tests

产品编号：130-099-688 品牌：MACS美天旎原厂货号：130-099-688
产品分类：抗体 > 一抗 > 染料标记抗体
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描述：

CD324, also known as E-Cadherin or cadherin-1, is a calcium dependent cell adhesion protein found in adherence junctions of epithelial cells, e.g., in colon, uterus, liver, keratinocytes etc. E-Cadherin also serves as a ligand for integrin alpha-E/beta-71. The epitope is expressed by a variety of carcinoma-derived cell lines such as MCF-7, HT-29, T-47D, NTERA-2, and 2102Ep. Loss of E-Cadherin is thought to enable metastasis by disrupting intercellular contacts—an early step in metastatic dissemination2. Furthermore, E-Cadherin is a marker of undifferentiated embryonic stem (ES) cells and induced pluripotent stem (iPS) cells3,4. For these cells, E-Cadherin plays a major role in conveying cell survival signals5.

原厂资料：

CD324, also known as E-Cadherin or cadherin-1, is a calcium dependent cell adhesion protein found in adherence junctions of epithelial cells, e.g., in colon, uterus, liver, keratinocytes etc. E-Cadherin also serves as a ligand for integrin alpha-E/beta-71. The epitope is expressed by a variety of carcinoma-derived cell lines such as MCF-7, HT-29, T-47D, NTERA-2, and 2102Ep. Loss of E-Cadherin is thought to enable metastasis by disrupting intercellular contacts—an early step in metastatic dissemination2. Furthermore, E-Cadherin is a marker of undifferentiated embryonic stem (ES) cells and induced pluripotent stem (iPS) cells3,4. For these cells, E-Cadherin plays a major role in conveying cell survival signals5.

注意事项：

Reagents contain sodium azide. Under acidic conditions sodium azide yields hydrazoic acid, which is extremely toxic.Azide compounds should be diluted with running water before discarding. These precautions are recommended to avoid deposits in plumbing where explosive conditions may develop.