The Anti-Slan (M-DC8) antibody (clone DD-1) recognizes Slan (6-Sulfo LacNAc), which is a carbohydrate modification of P-selectin glycoprotein ligand-1 (PSGL-1). This antigen is characteristically expressed on a new subset of peripheral blood mononuclear cells (PBMCs) with features closely related to CD16+CD14lowmonocytes.
Slan (M-DC8)+cells constitute 0.5–2% of all PBMCs with similar frequencies among mononuclear cells from cord blood.
原厂资料:
The Anti-Slan (M-DC8) antibody (clone DD-1) recognizes Slan (6-Sulfo LacNAc), which is a carbohydrate modification of P-selectin glycoprotein ligand-1 (PSGL-1). This antigen is characteristically expressed on a new subset of peripheral blood mononuclear cells (PBMCs) with features closely related to CD16+CD14lowmonocytes.
Slan (M-DC8)+cells constitute 0.5–2% of all PBMCs with similar frequencies among mononuclear cells from cord blood.