The Mouse IgG1 isotype control antibody clone IS5-21F5 is specific for KLH (keyhole limpet hemocyanin). This protein is not expressed on human cells or cell lines. Therefore, the antibody clone IS5-21F5 can be used as a negative control, to distinguish specific from non-specific binding of mouse IgG1 fluorochrome-conjugated antibodies to human cells, for example via Fc receptors, or due to interactions of the fluorochrome with the cell surface.
原厂资料:
The Mouse IgG1 isotype control antibody clone IS5-21F5 is specific for KLH (keyhole limpet hemocyanin). This protein is not expressed on human cells or cell lines. Therefore, the antibody clone IS5-21F5 can be used as a negative control, to distinguish specific from non-specific binding of mouse IgG1 fluorochrome-conjugated antibodies to human cells, for example via Fc receptors, or due to interactions of the fluorochrome with the cell surface.