Clone AF12-7H3 recognizes the human CD56 antigen, a glycoprotein of the Ig-superfamily also known as neural cell adhesion molecule (NCAM) which is expressed in blood on practically all resting and activated NK cells and on a minor subset of CD3+ T cells. CD56 is reported to be expressed on rhesus monkey monocytes but not on NK cells.1
CD56 is also expressed in brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal-derived tumors, myelomas, and myeloid leukemias also express CD56.
The monoclonal antibody AF12-7H3 recognizes an epitope distinct from those recognized by the CD56-specific mAbs NCAM16.2 and B159.
原厂资料：
Clone AF12-7H3 recognizes the human CD56 antigen, a glycoprotein of the Ig-superfamily also known as neural cell adhesion molecule (NCAM) which is expressed in blood on practically all resting and activated NK cells and on a minor subset of CD3+ T cells. CD56 is reported to be expressed on rhesus monkey monocytes but not on NK cells.1
CD56 is also expressed in brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal-derived tumors, myelomas, and myeloid leukemias also express CD56.
The monoclonal antibody AF12-7H3 recognizes an epitope distinct from those recognized by the CD56-specific mAbs NCAM16.2 and B159.
京公网安备11010802025653 版权所有：北京逸优科技有限公司
