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CD197 (CCR7)-PE, human 30 tests

  • 产品编号:130-098-124      品牌:MACS美天旎       原厂货号:130-098-124
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
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运保温度: 2−8 °C
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描述:

CCR7 is a chemokine receptor with a C-C motif that mediates homing of T cells to secondary lymphoid organs via high endothelial venules (HEV). For example, naive T cells migrate very efficiently through lymph nodes using the adhesion molecules L-selectin, CD62L, and CCR7. Ligands for CCR7, e.g. CCL19, are expressed by the HEV of secondary lymphoid organs, by parenchymal cells within T cell zones of lymph nodes, and by endothelial cells at the openings of lymphatic vessels within peripheral tissues. Expression of CCR7 and the CD45RA isoform distinguishes three subsets of T cells: naive T cells (CCR7+CD45RA+), central memory T cells (CCR7+ CD45RA), and effector memory T cells (CCR7 CD45RA).


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