CD197 (CCR7)-PE, human 30 tests

产品编号：130-098-124 品牌：MACS美天旎原厂货号：130-098-124
产品分类：抗体 > 一抗 > 染料标记抗体
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描述：

CCR7 is a chemokine receptor with a C-C motif that mediates homing of T cells to secondary lymphoid organs via high endothelial venules (HEV). For example, naive T cells migrate very efficiently through lymph nodes using the adhesion molecules L-selectin, CD62L, and CCR7. Ligands for CCR7, e.g. CCL19, are expressed by the HEV of secondary lymphoid organs, by parenchymal cells within T cell zones of lymph nodes, and by endothelial cells at the openings of lymphatic vessels within peripheral tissues. Expression of CCR7 and the CD45RA isoform distinguishes three subsets of T cells: naive T cells (CCR7⁺CD45RA⁺), central memory T cells (CCR7⁺ CD45RA^–), and effector memory T cells (CCR7^– CD45RA^–).

原厂资料：

CCR7 is a chemokine receptor with a C-C motif that mediates homing of T cells to secondary lymphoid organs via high endothelial venules (HEV). For example, naive T cells migrate very efficiently through lymph nodes using the adhesion molecules L-selectin, CD62L, and CCR7. Ligands for CCR7, e.g. CCL19, are expressed by the HEV of secondary lymphoid organs, by parenchymal cells within T cell zones of lymph nodes, and by endothelial cells at the openings of lymphatic vessels within peripheral tissues. Expression of CCR7 and the CD45RA isoform distinguishes three subsets of T cells: naive T cells (CCR7⁺CD45RA⁺), central memory T cells (CCR7⁺ CD45RA^–), and effector memory T cells (CCR7^– CD45RA^–).

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仅用于科研