The CD8 antigen forms a complex with the T cell receptor and acts as an accessory molecule in the recognition of MHC class I/peptide complexes by the TCR heterodimer on CD8+ cytotoxic T cells. The CD8 molecule consists of either an α/β heterodimer or an α/α homodimer. It is strongly expressed on cytotoxic T cells and dimly on a subset of NK cells. CD8 is expressed on most thymocytes and on about one，third of all peripheral blood T cells. CD8+ cytotoxic T cells play an important role in the killing of virus-infected cells and tumor cells.
原厂资料：
The CD8 antigen forms a complex with the T cell receptor and acts as an accessory molecule in the recognition of MHC class I/peptide complexes by the TCR heterodimer on CD8+ cytotoxic T cells. The CD8 molecule consists of either an α/β heterodimer or an α/α homodimer. It is strongly expressed on cytotoxic T cells and dimly on a subset of NK cells. CD8 is expressed on most thymocytes and on about one，third of all peripheral blood T cells. CD8+ cytotoxic T cells play an important role in the killing of virus-infected cells and tumor cells.
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