CD117 MicroBeads are developed for the isolation of murine progenitor cells. CD117, also known as c-kit, steel factor receptor, and stem cell factor receptor, encodes a 145 kD cell surface glycoprotein belonging to the class III receptor tyrosine kinase family. It is expressed on the majority of hematopoietic progenitor cells, including multipotent hematopoietic stem cells as well as committed myeloid, erythroid, and lymphoid precursor cells. In addition to the hematopoietic cell differentiation potential, CD117+ stem cells from murine bone marrow were reported to be capable of differentiation into smooth muscle cells, myocytes, and endothelial cells in vivo.¹,² CD117 is also expressed on a few mature hematopoietic cells, for example, mast cells.
原厂资料：
CD117 MicroBeads are developed for the isolation of murine progenitor cells. CD117, also known as c-kit, steel factor receptor, and stem cell factor receptor, encodes a 145 kD cell surface glycoprotein belonging to the class III receptor tyrosine kinase family. It is expressed on the majority of hematopoietic progenitor cells, including multipotent hematopoietic stem cells as well as committed myeloid, erythroid, and lymphoid precursor cells. In addition to the hematopoietic cell differentiation potential, CD117+ stem cells from murine bone marrow were reported to be capable of differentiation into smooth muscle cells, myocytes, and endothelial cells in vivo.¹,² CD117 is also expressed on a few mature hematopoietic cells, for example, mast cells.
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