CD11b MicroBeads, human, mouse

• 产品编号：130-049-601      品牌：MACS美天旎       原厂货号：130-049-601
• 产品分类：生化和细胞分析 > 微珠和磁珠 > 细胞分选磁珠 > 分离人细胞
• 应用分类：

描述：

CD11b MicroBeads were developed for the isolation or depletion of human and mouse cells based on their CD11b expression.

原厂资料：

Background information

In humans, CD11b is strongly expressed on myeloid cells, and weakly expressed on NK cells and some activated lymphocytes.
In mice, the CD11b antigen is expressed on monocytes/macrophages and to a lower extent on granulocytes, NK cells, CD5+ B1 cells, and a subset of dendritic cells.

Downstream applications

In humans, CD11b MicroBeads can be used for positive selection or depletion of CD11b+ cells from PBMCs, bone marrow, and other lymphoid tissues. They are mostly used in combination with other MicroBeads for depletion of unwanted cells.
In mice, CD11b MicroBeads have been used to isolate CD11b+ cells from cell suspensions of spleen1, lymph node2, peritoneal cavity3, liver4, muscle tissue2, or blood5. They were also used in combination with other MicroBeads for the enrichment of mast cells from peritoneal cell suspensions.3
For the isolation of human monocytes CD14 MicroBeads or the Pan Monocyte Isolation Kit are recommended.

Columns

For positive selection: MS, LS, XS, or autoMACS® Columns. For depletion: LD, CS, D, or autoMACS Columns.

注意事项：

Reagents contain sodium azide. Under acidic conditions sodium azide yields hydrazoicacid, which is extremely toxic. Azide compounds should be diluted with running water before discarding. These precautions are recommended to avoid deposits in plumbing where explosive conditions may develop.