Human Activin A

• 产品编号：120-14-5ug      品牌：Peprotech       原厂货号：120-14
• 产品分类：蛋白质检测与分析 > 蛋白质，多肽和酶 > 细胞因子和生长因子 > TGF-beta 转化生长因子beta超家族
• 应用分类：

描述：

激活素A是TGF-β家族成员表现出广泛的生物活性，包括细胞增殖和分化，以及促进神经元存活的调节。激活素A在患有结肠直肠肿瘤的人和绝经后妇女的体内含量升高，分别与大肠癌和乳腺癌的发生有关。激活素A的生物活性可以通过抑制素和由扩散型TGF-β拮抗剂（卵泡抑素）被中和。人/小鼠/大鼠激活素A 26.0 kDa，是由二硫键连接两个βA链的同型二聚体，每条链含116个氨基酸残基。

原厂资料：

Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in post-menopausal woman have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, Follistatin. Human/Murine/Rat Activin A is a 26.0 kDa disulfide-linked homodimer of two β A chains, each containing 116 amino acid residues. *Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

注意事项：

仅用于研究。不适用于诊断或治疗。