Description: The monoclonal antibody MIG-2F5.5 reacts with mouse monokine induced by IFN gamma (mig, mig-1, CXCL9). This 14.4 kDa inflammatory chemokine is specifically induced by IFN gamma, but not other activators such as LPS or IFN alpha. Secretion of mig, mainly by macrophages results in the chemotaxis of a variety of activated T cells via the CXCR3 chemokine receptor. Mig is involved many areas of research including autoimmune diseases, cancer, and inflammation.
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