Description: The monoclonal antibody reacts with human CD119 also known as the IFN-γ receptor 1 (alpha chain). IFN γR1 is found in a complex with IFN-γ receptor beta and recognizes with high affinity IFNγ. Expression is ubiquitous but low, although some cell types, such as monocytes express higher levels.
The GIR-208 monoclonal antibody is blocked from binding when IFNγ is bound to the receptor.