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ANTI-MO CD40 1C10 PE 50UG

  • 产品编号:12-0401-81      品牌:invitrogen       原厂货号:12-0401-81
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
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运保温度: 2-8℃
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描述:

Description: The 1C10 monoclonal antibody reacts with mouse CD40, a 45-50 kDa type I transmembrane glycoprotein. CD40 is a member of the TNFR family and is expressed by mouse B lymphocytes, follicular dendritic cells, thymic epithelium, and a subset of peripheral T cells. CD40 regulates B cell development/maturation by inducing Ig isotype switching and in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with CD154 (gp39), its ligand on T cells, is important in T-B cell crosstalk and plays a role in costimulation and immune regulation.


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