Description: The T3.70 monoclonal antibody reacts with the transgenic αβTCR that recognizes the male antigen H-Y in the context of H-2Db. A large fraction of T cells in H-Y TCR transgenic mouse expresses this receptor. The H-Y TCR transgenic mouse has been used extensively to study T cell development and the role of thymic major histocompatibility complex in CD4+ and CD8+ T cell differentiation.