HUMAN SCD22- PEPROTECH

• 产品编号：100-01-100ug      品牌：Peprotech1       原厂货号：100-01-100UG
• 产品分类：蛋白质检测与分析 > 蛋白质，多肽和酶 > CD因子及其它细胞表面标记分子
• 应用分类：

描述：

CD22是B谱系限制的135 kDa的糖蛋白，其细胞表面表达的静止和激活被B淋巴细胞所限制。 CD22的生理作用仍未知。在小鼠中做CD22靶向破坏的结果显示外周B细胞表面的IgM减少，说明CD22在限制抗原受体信号的过程中发挥作用。 CD22是唯一地结合的唾液酸依赖配体的免疫球蛋白基因超家族的成员。重组人CD22是对应于CD22胞外域的75.0 kDa可溶性的蛋白质。

原厂资料：

CD22 is a B-lineage restricted 135 kDa glycoprotein whose cell surface expression is limited to resting and activated B lymphocytes. The physiological role of CD22 is still unknown. Targeted disruption of CD22 in mice results in a reduced level of surface IgM on peripheral B cells suggesting a role for CD22 in limiting antigen receptor signaling. CD22 is a member of the Ig gene superfamily that uniquely binds a sialic acid-dependent ligand. Recombinant human CD22 is a soluble 75.0 kDa protein which corresponds to the extracellular domain of CD22.

注意事项：

仅用于研究。不适用于诊断或治疗。