ApplicationsSpecinomycin is used in cell culture applications, It is active against gram-negative bacteria. It is also used for the treatment of gonorrhea. As a selection agent for transformed plant cells that contain the selectable marker gene Spcr.
Product DescriptionSpectinomycin is an aminocyclitol antibiotic, closely related to the aminoglycosides, it inhibits protein synthesis (elongation) by interfering with peptidyl tRNA translocation. Mutation in rpsE (the gene for ribosomal protein S5) prevents binding of spectinomycin.
Biochem/physiol ActionsAntimicrobial spectrum: Gram-negative and Gram-positive bacteria (Gonnococcus only). Inhibits protein synthesis. Mutation in ribosomal protein S5 prevents binding of spectomycin.
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