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描述:
Synonyms β-NADPH; TPNH; Coenzyme II reduced form tetrasodium salt; Dihydronicotinamide-adenine dinucleotide phosphate tetrasodium salt; Triphosphopyridine nucleotide reduced tetrasodium salt
Product Description
β-NADPH is a product of the pentose phosphate pathway, a multifunctional pathway whose primary purpose is to generate reducing power in the form of β -NADPH. β-NADPH transfers H+ and 2 e- to oxidized precursors in the reduction reactions of biosynthesis. Thus, β-NADPH cycles between catabolic and biosynthetic reactions and serves as the carrier of reducing power in the same way that ATP serves as the carrier of energy. β-NADPH is also involved with Cytochrome P450 electron transport systems. Enzymes using β-NADPH as a coenzyme include glutathione reductase, diacetyl reductase, dihydrofolate reductase, glutamic dehydrogenase, p-hydroxybenzoate hydroxylase, NADPH-FMN oxidoreductase, nitrate reductase and thioredoxin reductase.
Applications
β-NADPH is a coenzyme found in all living cells and is involved in redox reactions carrying electrons from one reaction to another
Biochem/physiol Actions
Electron donor; cofactor for many redox enzymes including nitric oxide synthetase.